The recommended dosage of venlafaxine varies depending on the condition being treated, the patient's response to the medication, and their overall health. For adults with major depressive disorder, the typical starting dose of immediate-release venlafaxine is 75 mg per day, divided into two or three doses. This can be increased by the healthcare provider in increments of up to 75 mg every four days, depending on the patient's response and tolerability. The maximum recommended dose for most patients is 225 mg per day, although some individuals may be prescribed up to 375 mg per day in divided doses for more severe cases.
For generalized anxiety disorder, social anxiety disorder, and panic disorder, the starting dose of extended-release venlafaxine is usually 37.5 mg to 75 mg once daily. This dose may be increased by the healthcare provider as needed, typically in increments of 75 mg per day, with a usual maximum dose of 225 mg per day for anxiety disorders and 225-375 mg per day for panic disorder.
It is important for patients to follow their healthcare provider's instructions and not to adjust the dosage on their own. Venlafaxine should be taken with food to help reduce gastrointestinal side effects, and the extended-release capsules should be swallowed whole, not crushed, chewed, or dissolved. Abruptly stopping venlafaxine can lead to withdrawal symptoms, so any changes in dosage should be done gradually under medical supervision. As with all medications, individual responses can vary, so close monitoring by a healthcare provider is crucial to ensure safe and effective treatment.