St. John's Wort should not be taken with fluoxetine. Combining St. John's Wort, a popular herbal supplement often used to treat depression and anxiety, with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can lead to a dangerous condition known as serotonin syndrome. This condition results from excessive serotonin in the brain and can cause symptoms such as confusion, agitation, rapid heart rate, high blood pressure, dilated pupils, loss of muscle coordination, or even severe complications like seizures or unconsciousness. Both St. John's Wort and fluoxetine increase serotonin levels, so their simultaneous use amplifies the risk of serotonin syndrome. To ensure safe and effective treatment, it is crucial to consult with a healthcare provider before combining any herbal supplements with prescription medications, particularly those that affect neurotransmitter levels.
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18 july 2024 (05:45)
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