Trental (Pentoxifylline)

What is Generic Trental?

The drug Generic Trental relates to medicaments which allow you to quickly and effectively eliminate the spasm of the vascular bed and restore the normal pressure level. Dilation achieved 30 minutes after administration of tablets and continues for 6 hours.

The active ingredient belongs to the chemical group of purines. These components have antispasmodic effect. Besides are improved rheological parameters. Due to its composition the drug improves blood flow and elasticity of red blood cells, reducing the unification processes of platelets, reduces blood viscosity. Also, when receiving Trental are reduced plasma concentrations of plasminogen and this leads to improved flow of fibrinolysis (the dissolution of blood and clots). Microcirculation in the smallest capillaries occurs by improving the blood flow conductivity. Gradually is produced capacity of ATP energy potential inhibitors in the cell structure of the mucosa and muscle layer of the vascular bed. It has the positive impact on the provision of myocardial red blood cells and oxygen. In this case there is no increase in heart rate at the positive dynamics of the increase in the volume of blood ejected from the heart muscle. After 72 hours from the first administration of the drug improves the structure of ATP generation in all parts of the brain. In particular the highest drug concentration observed in areas where there are circulatory disorders.

In what kind of disease treatment Trental is helpful?

Generic Trental tablets are appointed in various diseases. Etiology of development has impaired vascular tone. The drug has the following indications for use:

• obliterating and occlusive endarteritis;
• diabetic angiopathy nature;
• intermittent claudication;
• trophic skin lesions on a background of thrombophlebitis and thrombosis;
• hemorrhoidal lesion of the rectum;
• stagnation in the pelvic cavity;
• gangrene on the background of frostbite or thermal impact of negative factors.

Also, the drug can be used in various forms of cerebral blood flow in acute, transient and chronic stage. In cerebrovascular tablets improve the regeneration of tissues, restores mental processes and increases the ability to memorize a long-term and short-term events. It reduces the intensity of headaches, reduced convulsions.

In andrology drug used actively with impotence therapy based on violations of vascular origin. Chronic obstructive pulmonary processes on the basis of bronchial asthma can also be indications for the use of pharmacological agents to improve the processes of ventilation pulmonary alveoli and their arterial blood supply.

Reviews of Generic Trental show the efficiency in therapy of heart disease. A particularly successful application at:

• myocardial infarction;
• chronic cardiovascular insufficiency;
• coronary heart disease;
• atherosclerotic lesions of large coronary vessels.

In the treatment of retinal diseases are used as an aid to improve trophism and tissue regeneration.

What should I tell my health care provider before I take Generic Trental?

Contraindications for treatment of Generic Trental include:

• during pregnancy and breastfeeding;
• reduction of blood clotting time;
• reduction of platelets in the blood;
• porphyria;
• gastric ulcer and duodenal ulcer;
• bleeding in any brain structures and retina of the eye;
• acute myocardial infarction and acute stage;
• patients with hypersensitivity to the drug.

How should I take Trental?

To take the pills you should only in its entirety without violating the integrity of the enteric coating. Maintenance treatment should be carried out within 2 - 3 months.

Dosage information

Initial dosage of 600 mg per day and is divided into 3 doses. Intensive Care - 1200 mg per day, divided into 3 parts number. Maintenance period is 300 mg per day. Also you should read the instruction if you buy Generic Trental without prescription.

What may interact with Generic Trental?

If you purchase Generic Trental online then you should know that it is able to significantly increase the effects of drugs against hypertension and efficacy of insulin-containing medicines. In concomitant administration of this drug with Ketorolac and Meloxicam significantly increased the level of risk of bleeding. In an application with Cimetidine it increases the level of probability of side effects.

What should I watch for while taking Trental?

To avoid symptoms of side effects of Generic Trental and achieve maximum effectiveness in the treatment of drug, it is necessary to adhere strictly to the dosage and course of treatment prescribed by the attending specialist.

What side effects may I notice from Generic Trental?

Most often undesired reactions from taking this medication are not critical. Side effects for which you need to stop taking the drug are rare. Side effects from the drug therapy should include general weakness, recurrent headaches, thinning of nails, hair deterioration, bleeding, weight gain, increased sweating, "tides" of blood to the skin of upper chest and face skin. They usually begin to appear in violation of dosing regimens and chronic administration of the drug. It may be a violation of liver and kidney function with higher rates of biochemical blood tests which include transaminases, creatinine, bilirubin.

Among the side effects that can cause reception of Pentoxifylline are considered to be more common manifestations such as:

• nervous condition;
• drowsiness;
• insomnia;
• arrhythmia;
• intestinal atony;
• aggravation of cholecystitis;
• tachycardia;
• angina;
• swelling;
• increased concentrations of liver enzymes;
• leukopenia;
• bleeding;
• pancytopenia;
• allergic reactions such as urticaria.

Where can I keep Trental?

Keep the drug in a dry place. Don’t let kids play with it. It is possible to buy Generic Trental online.