Tadapox works in the body through its two active ingredients, tadalafil and dapoxetine, which have distinct mechanisms of action:
Tadalafil: Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. It primarily works by blocking the action of PDE5 enzyme in the smooth muscle cells of the penis. Normally, PDE5 enzyme breaks down a substance called cyclic guanosine monophosphate (cGMP), which is responsible for relaxing the smooth muscles and increasing blood flow to the penis during sexual stimulation. By inhibiting PDE5, tadalafil helps to maintain higher levels of cGMP, which promotes prolonged relaxation of the penile arteries and enhances blood flow. This results in improved erectile function, allowing a man to achieve and maintain an erection sufficient for sexual activity.
Dapoxetine: Dapoxetine is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the activity of serotonin in the nervous system. Serotonin is a neurotransmitter involved in regulating mood, emotions, and the ejaculatory process. Dapoxetine inhibits the reuptake of serotonin, which prolongs the action of serotonin at the synaptic clefts (gaps between nerve cells). This delay in serotonin reuptake helps to improve control over ejaculation and delay the onset of ejaculation during sexual activity, thus treating premature ejaculation.
By combining tadalafil and dapoxetine in Tadapox, the medication addresses both erectile dysfunction (ED) and premature ejaculation (PE) simultaneously. Tadalafil enhances erectile function by improving blood flow to the penis, while dapoxetine improves control over ejaculation by delaying the ejaculatory reflex. This dual action aims to enhance sexual performance and satisfaction in men experiencing both conditions.