Canasa (Mesalamine)

What is Canasa?

Canasa rectal candles are an effective remedy for the treatment of ulcerative colitis, proctosigmoiditis and proctitis, as well as other similar diseases. Sometimes it makes sense to use such a drug in the form of not only candles, but also tablets. The attending physician should help in choosing.

Like any drug, Canasa has a high degree of effectiveness, if the therapy is carried out correctly. Therefore, it is necessary to treat extremely carefully the use of this medication so as not to harm the health and cure the existing disease.

First of all, it is necessary to understand how the drug works. Here is a special mechanism, which explains the high effectiveness of the drug. The main active component of the drug is Mesalamine. As a rule, it has the strongest anti-inflammatory effect, since an active synthesis of lipid substances takes place. And yet Mesalamine is able to stop the process of phagocytosis and inhibit the production of immunoglobulins. Due to this, the body copes much better with diseases.

The unique ability of Mesalamine is an active antioxidant effect. This substance binds to free oxygen radicals, gradually leading to their destruction. Scientists have long proven that this even prevents the emergence of malignant neoplasms in the body.

The greatest activity of Canasa is manifested in the lumen of the large intestine. It is there that the active substance is best absorbed by the body. With the simultaneous use of tablets containing Mesalamine, the medicine is also absorbed by the small intestine, the walls of the stomach.

In what kind of disease treatment, Canasa is helpful?

It is necessary to consider the indications for the use of this medicine for the diseases of the gastroenterological tract. There are three main diseases that are perfectly cured by such a drug. Let's look at these diseases and their manifestations in more detail.

Crohn's disease is a rare but very terrible disease. It is characterized by a gradual lesion of the entire gastrointestinal tract. But most of all the ileum is affected. Symptoms of Crohn's disease are diarrhea, in which there is blood in the stool, a weakening in immunity and intoxication of the body. Often, severe abdominal pain can resemble pain in appendicitis. Therefore, it is necessary to use Canasa 500mg for treatment when the doctor makes this diagnosis.

Another disease is ulcerative colitis. It is especially good to use these suppositories in the nonspecific form of colitis. With this disease on the mucosa of the colon appear numerous ulcers, it can be swollen. As a result, the process of defecation is also significantly complicated. Ulcerative colitis is usually accompanied by lowering of the human immune system, so it is very important, besides these suppositories, to use additional drugs and vitamins.

Canasa treat also different forms of diverticulitis. This is an excellent prevention against colon cancer. It is especially important from time to time to take such candles to people who have a hereditary predisposition to oncological diseases.

What should I discuss with my healthcare provider before taking Canasa?

This medicine has a lot of contraindications (a qualified specialist can list them all for you), and it is important not to use it independently, without doctor’s prescription. There are several diseases that can get worse if you take Canasa candles.

Hemorrhagic diathesis is a disease in which in no case you should use Canasa. This is due to the fact that there may be increased bleeding from the rectum. Vessels become very weak. Also, doctors do not recommend treating people who have blood diseases with these candles. In any case, you should always consult with your doctor and undergo preliminary tests.

Pregnant women and especially mothers who are breastfeeding their children should be very careful. The presence of Mesalamine in breast milk has a bad effect on the baby.

One shouldn’t take these candles for treatment if there are digestive system ulcers, all kinds of kidney or liver pathologies. Lack of glucose in the body can become even more severe if you take this medicine. And, of course, Canasa is not suitable for treating children under 2 years old.

Before buying this drug, make sure that such treatment will be useful for you. Only after that you can buy this medicine in your local pharmacy or buy Canasa online without prescription.

How should I take Canasa?

It is highly recommended to use this product just before bedtime. It is important to wash yourself with warm water and soap and rinse with cool water.

When using these rectal candles, often there are spasm in the stomach and urge to defecate, so before the procedure, perform a cleansing enema or empty the intestine naturally. Otherwise, the candle may not have time to dissolve and the result of treatment will equal zero. No additional manipulations are required before using them.

Your hands should be very clean so that germs do not get inside the body. The procedure should be carried out in full cleanliness. Prepare wet wipes or a damp handkerchief.

Lie on your side, pressing your knees to the belly. For the procedure, this posture is most convenient, since it allows you to minimize unpleasant sensations.

Remove the candle from the package and push it with your finger into the anal aperture to a depth of 2-3 cm. Do it gently, without causing excessive pressure. Despite the fact that the suppository has a streamlined form, imprudent use can injure the mucous membrane.

Do not get out of bed for about 20 minutes, so much time is required so that the suppository, under the influence of heat of the body temperature, is dissolved and absorbed. Wipe the hands with the damp wet wipes or handkerchief.

If within 10 minutes after the rectal candle was introduced, you want to go to the toilet, empty the intestine and use a new suppository. Most likely, the first candle did not have time to absorb, and therefore does not make sense to expect the expressed effect of treatment. If between suppository administration and defecation has passed more than 10 minutes, an additional dose of a medicine is not required. In this case, it is almost impossible to calculate the amount of medicine taken, and therefore there is a risk of overdose.

Canasa dosage information

As a rule, most often preference is given to Canasa rectal candles, not tablets. The explanation is simple: there is no effect on the gastric mucosa. The usual weight of one candle is 500 mg. But it is recommended to start treatment with a dose of 250 mg. So, the risk of side effects decreases.

The maximum period of treatment with this medicine should last no more than 3 months. This is provided that large dosages of the drug are taken. The minimum treatment time is a week. Usually this is enough to prevent many diseases.

Proper introduction of suppositories into the rectum at dosages prescribed by the doctor is already half the successful treatment. Relative cheapness of Canasa and ease of use make it possible to apply it to almost all categories of people. Generic Canasa costs even cheaper. It is sold in many traditional drugstores or one may buy generic Canasa online.

What may interact with?

Canasa causes an increase in the effect of anticoagulants, derivatives of sulfonylureas, increases the toxicity of methotrexate. The drug reduces the tuberculostatic effect of rifampicin, the uricosuric effect of probenecid and sulfinpyrazone and the diuretic effect of spironolactone and furosemide.

What should I watch for while taking Canasa?

As for the peculiarities of using these rectal candles, they can be strictly individual for each patient. Only a doctor can correctly determine them. Much will depend on where the disease is localized, in which part of the intestine it progresses more.

The drug does not directly affect the brain activity, nevertheless, against the background of its use, it is not recommended to perform work that is associated with increased concentration of attention and being able to make urgent decisions.

Canasa side effects

This medication sometimes causes side effects. They can be expressed in various allergic reactions on the skin (itching, rashes, lupus or urticaria), in myocarditis, fever. This often happens when there is an individual intolerance to the main active substance of the suppository.

The most common negative reactions are flatulence, indigestion (as a temporary phenomenon), convulsions, a depressive state, accompanied by dizziness, general weakness of the body and noise in the ears. Very rarely there may be tachycardia, too high or too low blood pressure.

Where can I keep Canasa?

Keep out of the reach of children. Store at a temperature not higher than 30° C. Store in original packaging to protect the suppository from light. These candles can be stored in the refrigerator.

Before buying this drug, consult your gastroenterologist. This drug is sold practically in any pharmacy. You can also buy Canasa online at a cheap price. Such a purchase can be made, for example from Spain pharmacies online.