Imuran (Azathioprine)

What is Generic Imuran?

The result of receiving Generic Imuran can be noticeable over several days or weeks after start of therapy. Great risk of rejection during transplantation remains even after a couple of weeks after discontinuation of therapy with it. During the first 2 months of the course should be carried out weekly blood tests with counting platelets. With a sharp decrease in the number of leukocytes dosage is reduced while reducing the treatment should be discontinued.

In what kind of disease treatment Imuran is helpful?

This drug is able to inhibit tissue incompatibility reactions in and delayed-type hypersensitivity. Therefore it is suitable for diseases such as:

• Myasthenia gravis;
• Dermatomyositis;
• Crohn's disease;
• Nonspecific ulcerative colitis;
• Psoriasis, pemphigus vulgar;
• Chronic hepatitis in the stage of activity;
• Periarteritisnodosa;
• Systemic lupus erythematosus.

Generic Imuran can serve as a prophylactic to prevent rejection reactions after surgery to organ transplants.

What should I tell my health care provider before I take Generic Imuran?

For use there are a number of contraindications. These include the following diseases:

• High sensitivity to one of the components of the drug;
• Renal and liver failure;
• Aplastic anemia;
• Thrombocytopenia;
• During pregnancy and lactation;
• Children under the age of eighteen.

How should I take Imuran?

This medication should be taken internally. The attending physician in each individual case appoints Imuran dosage depending on the clinical picture and the patient's general condition. If you purchase Generic Imuran online all other information can be found in the instructions in the package.

Dosage information

As prophylaxis of rejection reactions this drug used with Cyclosporin and corticosteroids for reception with the following scheme: four milligrams per kg weight in two - three doses for seven days before surgery, and after two months with a gradual lowering of the dosage of two - three milligrams per kilogram of patient weight. If signs of graft rejection still occur, the daily dose of Azathioprine can be increased to four mg per kg of patient weight.

In other cases the drug is given for reception by a half - two milligrams per kg body weight per three - four stages.

What may interact with Generic Imuran?

Many drugs can interact with Generic Imuran so you should notify your doctor about all medicines that are taking or have taken in the last 3 months.

What should I watch for while taking Imuran?

Attention! Patients receiving the drug Generic Imuran are prohibited from being in the sun for a long time; they need to regularly inspect the skin; for patients with chronic diseases of the connective tissue is unacceptable without permission cancel treatment as this may cause an exacerbation of the main disease. The drug is prohibited for pregnant, because it can penetrate through placenta and adversely affect the fetus. In the first sixty days of receiving Azathioprine requires regular monitoring of peripheral blood. Monitoring is carried out every week through blood sampling for analysis. It is also necessary at this time to observe the hepatic functionality. Monitoring is carried out through regular liver function tests. Cancellation of the drug should not be harsh; it is overturned by gradual dose reduction.

What side effects may I notice from Generic Imuran?

Generic Imuran may cause side effects. The manifestations are as follows:

• as allergic reaction (myalgia, arthralgia, drug fever or skin rash);
• as gastrointestinal dysfunctions (nausea, vomiting, diarrhea, liver dysfunction, abdominal pain);
• after organ transplantation as ulcerative lesions, pancreatitis, intestinal necrosis and intestinal perforation;
• and other manifestations (infections, alopecia, meningeal reaction, interstitial pneumonia).

Where can I keep Imuran?

The storage place should be well protected against moisture, direct sunlight and children. The storage temperature corresponds to the room. Also there is a possibility to buy Generic Imuran online.