Wellbutrin Sr (Bupropion)

What is Generic Wellbutrin Sr?

Wellbutrin Sr is an antidepressant that is used to treat depressive disorders (including seasonal exacerbations). The substance is captured selectively by the dopamine transport, but the main effect of the medication is shown by inhibiting of the reuptake of norepinephrine. Also based on the formulations of bupropion are antagonists of nicotinic acetylcholine receptors. The drug significantly reduces seizure activity in the brain.

Any dependence of the body from external influences regarded as a human weakness. Perhaps one of the most widely is considered a nicotinic. To overcome it can help Wellbutrin Sr. You can find only positive reviews of this medicine. This is the first drug in the world that is designed to help to overcome nicotine addiction forever. The active substance Bupropion that is included into its structure affects the mechanisms in the brain that are responsible for pleasure; it replaces the "pleasure hormone", which gets people during the smoking. Thus, the patient does not experience discomfort during the period of quitting. Treatment results are shocking: it allows you to forget about smoking for 7-10 weeks.

In what kind of disease treatment Wellbutrin Sr is helpful?

• Treatment of depression;
• Prevention of depressive episodes repeats after successful primary treatment;
• Patients with obesity and sexual dysfunction in depression;
• The syndrome of deficiency of attention and seasonal affective disorder.

As the results of numerous studies show, this drug allows avoiding such negative effects of nicotine addiction, anger, anxiety, worry, frustration and irritability. In addition, those people who continue to take the drug even after they abandoned cigarettes have lower probability to start smoking again.

What should I tell my health care provider before I take Generic Wellbutrin Sr?

Doctors do not prescribe Wellbutrin Sr if patients have:

• Hypersensitivity to any component of the drug;
• Vascular disorders;
• During therapy with drugs, which include Bupropion;
• If the patient has a history of bulimia nervosa (a sharp increase in appetite) and anorexia (loss of significant body weight);
• in the case of receiving monoamine oxidase inhibitors (the enzyme);
• after the abrupt withdrawal of alcohol or sedative drugs;
• Children up to 18 years.

The impact of the drug on pregnancy and lactation has been insufficiently studied.

How should I take Wellbutrin Sr?

A tablet should be swallowed in whole form. In the treatment of nicotine addiction it must be taken in the morning before or after food. Such tablets can be administered no more frequently than once a day at the same time.

Dosage information

For adults doses treatment begins with no more than 150 mg per day (one tablet). Maximum Daily norm is 300 mg. However, with this increase the interval between doses of the drug should be at least 8 hours. The effect of the drug occurs only in a few weeks. In the presence of disorders in the functioning of the liver the drug should be used with caution. In severe cirrhosis of the liver should not be prescribed a daily dose of Wellbutrin Sr more than 150 mg / 48 hours.

Treatment in nicotinic addiction should be started a week before the day when you finally decide to give up nicotine (one tablet per day). On the eighth day of the course the dosage should be increased to two tablets in the morning and evening. In case you missed the reception, in any case, do not take two pills at once.

What may interact with Wellbutrin Sr?

When taking beta-blockers, metoprolol, antiarrhythmics, tricyclic antidepressants, antipsychotic drugs should be used minimally active and effective dosages. If the patient is already taking such a substance for some time then it is recommended to reduce the dosage.

The therapeutic effect may be affected by inhibitors of cytochrome P450 (Carbamazepine, Phenytoin). During clinical trials the effectiveness of the drug is reduced when combined with Ritonavir, Efavirenz and Lopinavir. Levodopa and Amantadine increases the likelihood of adverse reactions psychoneurotic.

What should I watch for while taking Wellbutrin Sr?

The risk of seizures and epileptic seizures increases with increasing dosage of the drug. Also seizures development is determined by certain risk factors: traumatic brain injury, epilepsy, a history of CNS tumors and parallel administration of drugs that reduce the seizure threshold. It is also recommended to abstain from alcohol, sedatives, hypoglycemic agents, insulin and medicines to reduce appetite.

Patients with hepatic failure should reduce frequency of use of the drug because this drug inhibits normal liver function.

It is not used in pediatric practice because of increased risk of suicidal thoughts and behavior in children and adolescents. Do not use during pregnancy or lactation.

What side effects may I notice from Generic Wellbutrin Sr?

The use of Wellbutrin Sr often causes side effects such as:

• Fever, pain in the chest, general weakness;
• Violation of the heart rate, increase in blood pressure, loss of consciousness;
• Possible sleep disorders, tremors in the limbs, diffuse attention, headaches, disturbances of orientation in space, depression, dizziness, irritability, anxiety, hallucinations, increased levels of aggression;
• Weight loss;
• Sensation of dryness in the mouth; constipation, pain in the abdomen;
• Skin rash, which may be accompanied by itching, increased sweating;
• Skin manifestations may be either mild (urticaria), and in more severe forms (vascular edema, bronchospasm, in rare cases, even anaphylactic shock);
• In some cases, may appear tinnitus, deterioration of visual function and taste buds.

To avoid symptoms of side effects and achieve maximum effectiveness in the treatment of drug it is necessary to adhere strictly to the dosage and course of treatment prescribed by the attending specialist.

Where can I keep Wellbutrin Sr?

Keep Wellbutrin Sr in a place out of reach of children, away from sunlight at the room temperature.