Seromycin (Cycloserine)

What is Seromycin?

Seromycin (operating ingredient — cycloserine) is a remedy that acts on mycobacterium. It has the bacteriostatic and bactericidal action, depending on the concentration of the medication at the site of inflammation and responsiveness of micro-organisms.

In what kind of disease treatment, Seromycin is helpful?

• Tuberculosis (chronic forms; Seromycin is a reserve medication, a part of combined therapy)
• Atypical mycobacterial infections (including those caused by Mycobacterium avium)
• Urinary tract infection

What should I tell my health care provider before I take Xylocain?

There are several signs that indicate the harmfulness and inexpediency of application of this kind of remedy, namely:

• Personal intolerance
• Organic CNS diseases
• Epilepsy
• Epileptic seizures (including in the anamnesis)
• Psychological disorders (anxiety, psychosis, depression, including in the anamnesis);
• Chronic heart insufficiency
• Chronic renal insufficiency (creatinine clearance less than 50 mL / min)
• Alcoholism

With a special care may be applied in kids.

Seromycin cannot be taken without serious indications (for "prevention", in viral ailments). An illiterate antibiotic therapy leads to the fact that among the bacteria, which in this particular case did not cause the sickness, remain resistant. As a result — they spread from person to person, causing a variety of difficult sicknesses.

How should I take Seromycin?

Take the capsules directly before the meals. An exception — if the antibiotic irritates your belly, it is best to take the capsules after meals. Action of antimicrobials, such as Seromycin, will be effective only if created the necessary concentration of the remedy in the organism. There are certain rules, which are important to follow to accomplish this task. Use of antibiotics should be strictly according to the scheme prescribed by the health care provider, and in accordance with his (her) recommendations. The preparation is taken as many times a day, as prescribed by the physician, at equal time intervals. In the instructions supplied with each medicine, are also indicated dosage and administration tips; such an instruction you can demand in your nearest drugstore, or you’ll get it when buying Seromycin online. One cannot independently increase or reduce the dosage suggested by the medical professional. Amount of a preparation is calculated individually for each diseased, taking into account his or her age and the presence of comorbidities. Use pure water at room temperature to wash down the medicine. Do not use tea or coffee, they accelerate the excretion of the drug, reducing the effectiveness of healing. Do not use juices. Juices contain phosphoric acid, which can react with the components of the formulation and cause poisoning.

Seromycin dosage information

Full grown persons: conventional intake makes 500 mg to 1000 mg per day in a few receptions. The starting intake for adults is most commonly 250 mg twice daily with 12-hour intervals for 2 weeks. The daily amount should not exceed 1 g.

Kids: The conventional intake is 10 mg / kg body weight per day in a few receptions and then this amount gets corrected depending on the concentration of the medicine in the plasma and therapeutic effect. The daily amount mustn’t exceed 750 mg.

Elderly patients: for patients aged 60 years and weighing less than 50 kg, the suggested intake makes 250 mg twice daily.

What may interact with?

Concurrent administration of Ethionamidum potentiates the neurotoxic effects of cycloserine.

Alcohol and cycloserine are incompatible, especially when taking large doses of the medicine.

Sick who are taking cycloserine and Isoniazid should be under the medical supervision, because this mixture may increase toxic effects on the central nervous system and the dose correction might be needed. Isoniazid increases the incidence of vertigo, sleepiness.

What should I watch for while taking Seromycin?

In the case of TB infection is necessary to determine the strain sensitivity to other anti-TB drugs.

In sick with impaired renal function that are receiving a daily dose of 500 mg, and in which presumably show signs and symptoms of an overdose, medicine levels in the blood must be controlled at least once a week.

For the prophylaxis of signs of central nervous system impairment, in particular, convulsions, tremors, or excitation state, use anticonvulsants or sedatives (with the permission of the health care provider).

Should be limited mental tensions and eliminates possible overheating factors (exposure to the sun with uncovered head, hot shower).

Due to the rapid development of resistance in cycloserine monotherapy is suggested its combination with other anti-TB drugs.

You should not stop the course of healing, it is important to observe the duration of the reception time. Improving the well-being cannot be the reason for self-withdrawal of Seromycin.

Give up tanning under the sun or solarium while taking Seromycin, and for two weeks after termination of treatment. Most antibiotics increase the skin's sensitivity to UV radiation.

Seromycin side effects

If you take Rx Seromycin in strict accordance with the doctor's guidelines, the likelihood of negative consequences is reduced to a minimum. Yet it still exists. Antibiotics are struggling not only with bacteria, which are currently triggered the infection, under attack are also those that live in the human organism and are not manifesting themselves in any way. Preferably therefore, the diseased may experience a variety of unwished reactions. Although they depend on the individual and the type of the bacteria, there are those that occur more frequently than others when taking Seromycin:

• Headache, dizziness, sleepiness or insomnia, nightmares, anxiety, irritability, memory loss, paresthesia, peripheral neuritis, tremor, euphoria, depression, suicidal tendencies, psychosis, epileptiform convulsions
• Exacerbation of chronic heart insufficiency in sick treated with 1 to 1.5 g of cycloserine per day
• Nausea, heartburn, diarrhea
• Skin rash, itching, megaloblastic anemia and increased levels of liver transaminases, nausea, heartburn, diarrhea, particularly in elderly patients with pre-existing hepatic disease
• Fever, increased cough

Where can I keep Seromycin?

Maximal retention period makes 2 years. Nevertheless, this period may be reduced significantly if you do not follow the simple tips for storage. It is crucial that the sun isn’t shining on the Seromycin package, so window sills and the dashboard of the car are not the best option. Also avoid environments with high humidity such as washrooms. If a capsule was removed from the original packaging and lay so for a long time it is better to throw it out; consuming of such a capsule may have unpredictable consequences. Storage temperature for the product should be less than 25°C. Purchase Seromycin at your regular drug store or buy Seromycin online at the lowest price.