Rhinocort (Budesonide)

What is Generic Rhinocort?

It is an active glucocorticoid that is used for treatment of allergic and inflammatory diseases of the respiratory tract. It belongs to long-acting drugs with the ability to single dosing. Consumption of glucocorticoids allows reducing the dose or completely abandoning the purpose of systemic corticosteroids.

The therapeutic effect of Rhinocort starts in about 6 hours after taking, a significant improvement in respiratory function observed in a few days. 34% of the applied dose is deposited in the lungs.

It reduces bronchial hyperreactivity, inhibits the early phase of allergic reactions (after prolonged use) and late phase response. Budesonide also reduces bronchial obturation caused by physical effort, cold air and sulfur dioxide.

About 90% of Budesonide is transformed in the liver to metabolites with very low bioactivity. The drug binds with plasma proteins by 86 - 90%, mainly with albumin. It is excreted with the urine (70%) and bile.

In what kind of disease treatment Rhinocort is helpful?

• Vasomotor rhinitis;
• Seasonal and allergic rhinitis;
• Prevention of the growth of nasal polyps after polypectomy (surgical removal of polyps).

This drug is used for the treatment of sarcoidosis, in cases of increased resistance to beta-mimetics and in cases of threat of pulmonary edema caused by the toxic effects of chlorine, phosgene and other toxic substances.

What should I tell my health care provider before I take Generic Rhinocort?

Your physician should know whether you have:

• Fungal, viral disease of the respiratory system and skin;
• Tuberculosis;
• Allergy to the active substance or any other drug.

Also aphonia is an absolute indication for discontinuation of Rhinocort.

During pregnancy you should use the lowest effective dose of Rhinocort. It is not known whether it gets into breast milk. The drug is contraindicated in children less than 2 years.

How should I take Rhinocort?

If you bought Rhinocort online and you have no other recommendations then use it twice a day - in the morning before breakfast and at night before bed. The basis of effective therapy is the proper application of the dosing device.

Insert the bottle tip into one of your nostril and close off the other one with a finger. While squeezing the bottle quickly breathe in. do the same process with other nostril.

Dosage information

Your doctor can help you to choose the most suitable dose, in other case follow the instructions which you can find in the package. Usually patients spray it twice, 100 mcg in each nostril.

What may interact with Rhinocort?

Cimetidine has a slight inhibitory effect on hepatic metabolism of Budesonide, but this phenomenon has no clinical significance. Clinically significant interactions with asthma drugs are not known.

Ketoconazole 200 mg which is taken once a day increased concentration of Budesonide in plasma (3 mg as single dose) by 6 times during their concomitant use. When patients used Ketoconazole 12 hours after Budesonide the concentration increased by 3 times. Since the data that would give recommendations about dosing are absent combinations of these drugs should be avoided. If not then you should do the interval between using of those two ingredients. It should also consider the possibility of reducing the dose. Other potent inhibitors such as Itraconazole, also lead to a significant increase active ingredient in plasma.

What should I watch for while taking Rhinocort?

Hoarseness of voice before therapy requires careful consideration because it may increase as a result of treatment.

The drug should be used with caution in patients with tuberculosis, mycosis lungs or respiratory tract viral infection. In the case of pulmonary mycosis is prescribed appropriate antifungal therapy. During withdrawal of oral corticosteroids and transfer to inhalation therapy patients require special attention to the complete restoration of the function of the hypothalamic-pituitary-adrenal function. The drug should be used during pregnancy only in cases where the opinion of the doctor is that the benefits to the mother outweigh any possible risk to the fetus.

Reduced liver function may affect the ability to excrete Budesonide.

The drug does not affect the psychological and physical characteristics, the ability to drive and control mechanisms.

Consumption of Rhinocort by athletes can have a positive test result for doping.

Patients should be informed about the need to consult with a doctor if the treatment effect will decrease.

What side effects may I notice from Generic Rhinocort?

Prolonged use of high doses may cause mycosis pharynx and larynx. Also it is possible to experience hoarseness of voice and dryness in the throat.

Cases of acute overdose are not described.

General disorders: angioedema.

Central nervous system: nervousness, anxiety, depression, behavioral disorders.

Skin: urticaria, rash, dermatitis, bruises.

Respiratory system: bronchospasm.

With prolonged use of high doses may cause systemic effects of glucocorticoids such as hypercorticoidism (edema, swelling of the face) and inhibition of the hypothalamic-pituitary-adrenal system.

Where can I keep Rhinocort?

Keep Rhinocort at temperature above 30 ° C, out of reach of children. Do not throw into the fire, even empty balloon. Keep away from direct sunlight. Do not store near heat sources. Do not freeze.