Clarinex (Desloratadine)

What is Generic Clarinex?

It is an antihistamine, II Generation H1 Histamine Receptor Blockers.

This is the main metabolite of Loratadine (antihistamine). Desloratadine, in turn, is metabolized to the active metabolite by enzyme that is not identified. 7% of the population has a reduced ability to metabolize Desloratadine, they are "poor metabolizers"; among black people it is 20%. Binding with protein is 82-89%, it eliminates from the body in 27 hours, for "poor metabolizers" - 50 hours. It inhibits series of allergic inflammation reactions: the release of cytokines, interleukins, chemokines, mediated by the release of prostaglandin D2.

It facilitates the allergic reactions, has antipruritic and anti-edema effect, reduces bronchial hyperreactivity, eliminates spasms of smooth muscles and reduces the severity of allergen-dependent bronchospasm.

In what kind of disease treatment Clarinex is helpful?

Clarinex is prescribed to people who suffer from allergic reactions. It can be seasonal and chronic hay fever (allergic to flowering and pollen) which is accompanied by inflammation of the mucosa, rhinitis, cough, lacrimation.

Also, the drug is used in skin dermatitis which can take place in conjunction with tissue edema, severe itching and unaesthetic appearance of the skin. Desloratadine perfectly relieves symptoms of idiopathic urticaria.

What should I tell my health care provider before I take Generic Clarinex?

Before you start to use the drug you should see a doctor and undergo skin tests to know for sure what exactly promotes manifestations of allergic reactions.

Desloratadine is not used when you have:

• Any hypersensitivity;

• Pregnancy;

• Breastfeeding;

• Children under 12 years of age;

• Malabsorption of glucose-galactose;

• Lactose intolerance;

• Rash, urticaria, angioedema;

• Headache, dizziness, insomnia, seizures, hallucinations;

• Fatigue;

• Tachycardia;

• Dry mouth, abdominal pain, nausea, diarrhea, elevated bilirubin levels;

• Myalgia;

• Lack of isomalt in the body.

How should I take Clarinex?

It is taken orally, preferably at the same time. The drug is independent of food intake. Swallow whole tablets. Duration is 24 hours.

Clarinex dosage information

Adults and children over 12 years: 5 mg 1 time per day. Clarinex is used in the same dosage and the same number of intakes.

Duration of consumption depends on the disease and the frequency of allergy symptoms. In intermittent rhinitis allergy symptoms that are experienced during less than 4 weeks in a year, treatment is complete after disappearance of symptoms and resume after they occur again. In persistent rhinitis allergy symptoms observed during more than 4 weeks in a year and relate to permanent contact with the allergen. In this case, the treatment is sustained until a patient end a contact with an allergen.

What may interact with Clarinex?

Interaction with other drugs that would have clinical significance hasn’t been identified. It does not also enhance the action of ethanol.

What should I watch for while taking Clarinex?

Avoid taking of this drug if you are expecting a baby because it is not known whether Desloratadine penetrate the placenta. Has no effect on the central nervous system even at a dose of 7.5 mg; no sedative effect, no effect on the rate of psychomotor reactions and no cardiotoxicity.

Well absorbed by the gastrointestinal tract, the lowest concentration found in the blood after half an hour and the maximum in 3 hours.

What side effects may I notice from Generic Clarinex?

Side Effects of Clarinex usually occur in people for whom this drug is not suitable. If the patients have noticed the following symptoms then it is necessary to suspend the treatment and replace it by another medicine. A patient can experience the following symptoms:

• Tachycardia;

• Dyspepsia;

• Severe dizziness;

• General weakness;

• Heartbeat;

• Vomiting;

• Hyperbilirubinemia;

• Anaphylactic shock;

• Nausea;

• Hyperthermia;

• Insomnia;

• Angioedema;

• Diarrhea.

It should be added that the above symptoms are rare but if the patient got one of them then it is necessary to cancel consumption of the pharmaceutical preparation.

Where can I keep Clarinex?

Shelf life is 2 years. Keep Clarinex in a dark and inaccessible to children place at temperature below 25 ° C. If you are looking for buy generic Clarinex online without prescription, so you must to choose best USA online pharmacy.